Forsteo ® (teriparatid)

För fullständig produktresumé för Forsteo® se FASS.

Denna information är endast avsedd för sjukvårdspersonal verksam i Sverige och som svar på din fråga. Informationen nedan är på engelska

Forsteo® (teriparatide): Patienter med cancerhistoria

Hos en patient med tidigare cancer, ta hänsyn till typen av cancer, risken för skelettmetastaser och hur lång tid patienten har varit i remission innan Forsteo föreskrivs.

Relevant Information from Summary of Product Characteristics

Patients with skeletal malignancies or bone metastases should be excluded from treatment with teriparatide (contraindication).1

Forsteo is contraindicated in patients with prior external beam or implant radiation therapy to the skeleton.1

Types of Common Cancer that Metastasize to the Bone

Common cancers that metastasize to the bone, in decreasing order of frequency, include2

  • breast

  • prostate

  • lung

  • colon

  • stomach

  • bladder

  • uterus

  • rectum

  • thyroid, and

  • kidney.

Note: This is not an all-inclusive list; cancers not included in this list may also have the potential to metastasize to the bone.

Information from Clinical Studies

Patients with a history of carcinoma in the previous five years or with a current suspicion were excluded from participating in clinical trials with teriparatide. However, patients with excised superficial lesions of the skin and those with a history of carcinoma in situ of the cervix or uterus were allowed to participate.3

There was no apparent increase in the incidence of cancers among all study participants treated with teriparatide compared with placebo during clinical trials.3

References

1. Forsteo [summary of product characteristics]. Eli Lilly Nederland B.V., The Netherlands.

2. File E, Deal C. Clinical update on teriparatide. Curr Rheumatol Rep. 2009;11(3):169-176. http://link.springer.com/article/10.1007/s11926-009-0023-3

3. Data on file, Eli Lilly and Company and/or one of its subsidiaries.

Datum fӧr senaste ӧversyn 2020 M03 03


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