Baqsimi ® (glukagon näspulver)

För fullständig produktresumé för Baqsimi® se FASS.

Denna information är endast avsedd för sjukvårdspersonal verksam i Sverige och som svar på din fråga. Informationen nedan är på engelska

Baqsimi® (glukagon näspulver): Pediatrisk dos

Det har fastställts att en enkeldos med 3 mg glukagon näspulver var lämplig för användning i hela åldersspannet 4 till <17 år.

Dosing in Children and Adolescents

NG is indicated for the treatment of severe hypoglycaemia in adults, adolescents, and children aged 4 years and over with diabetes mellitus.1

The recommended dose is 3 mg glucagon administered into one nostril.1

This is different from injectable glucagon which is dosed based on body weight in pediatric patients weighing less than 20 kg.2

The recommended dose of injectable glucagon for adults and pediatric patients weighing more than 20 kg is 1 mg given by SC, IM, or IV injection. For pediatric patients weighing less than 20 kg, the recommended dose is 0.5 mg or a dose equivalent to 20 to 30 mcg/kg.2

Pediatric Pivotal Study

A randomized, multicenter, dose finding clinical study evaluated the ability of NG 2 mg and 3 mg doses compared with injectable glucagon (0.5 mg or 1.0 mg based on body weight) administered IM to increase the BG after insulin-induced reduction in BG in children and adolescents (aged 4 to <17 years) with T1DM.3

The plasma glucose responses were similar, and adverse reactions occurred at a similar frequency and were transient with both the 2 mg and 3 mg doses of NG.3

It was determined that a single 3 mg NG dose was appropriate for use across the entire 4 to <17 year age range.3


1. Baqsimi [summary of product characteristics]. Eli Lilly Nederland B.V., The Netherlands.

2. Data on file, Eli Lilly and Company and/or one of its subsidiaries.

3. Sherr JL, Ruedy KJ, Foster NC, et al; T1D Exchange Intranasal Glucagon Investigators. Glucagon nasal powder: a promising alternative to intramuscular glucagon in youth with type 1 diabetes. Diabetes Care. 2016;39(4):555-562.


BG = blood glucose

IM = intramuscular

IV = intravenous

NG = nasal glucagon (glucagon nasal powder)

SC = subcutaneous

T1DM = type 1 diabetes mellitus

Datum fӧr senaste ӧversyn 2019 M10 03

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