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ZypAdhera® (olanzapine pamoate): Switch Between 2-weeks and 4-weeks Interval
Doses of 150 mg/2 weeks or 300 mg/4 weeks are recommended. Doses of 210 mg/2 weeks or 405 mg/4 weeks are recommended. There is no 4-week dose equivalent for doses of 300 mg/2 weeks.
should be treated initially with oral olanzapine before administering
olanzapine pamoate, to establish tolerability and response.1
order to identify the first olanzapine pamoate dose for all patients,
the scheme in Table 1
should be considered.1
1. Recommended dose scheme between oral olanzapine and olanzapine
oral olanzapine dose
starting dose of olanzapine pamoate
dose after 2 month of olanzapine pamoate treatment
or 405 mg/4 weeks
or 300 mg/4 weeks
or 405 mg/4 weeks
treatment, dose may subsequently be adjusted on the basis of
individual clinical status. After clinical reassessment, dose may be
adjusted within the range 150 mg to 300 mg every 2 weeks or 300 to
405 mg every 4 weeks (Table 1).1
full information on dosing please refer to the summary of product
ZypAdhera [summary of product characteristics] Eli Lilly Netherland
B.V., The Netherlands.
Date of Last Review:May 01, 2019
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