ZypAdhera ® (olanzapine pamoate monohydrate)

ZypAdhera® (olanzapine pamoate): Injection Site

Olanzapine pamoate is for deep intramuscular gluteal injection only. Do not administer intravenously or subcutaneously.

Detailed Information

Olanzapine pamoate should only be administered by deep intramuscular gluteal injection by a healthcare professional trained in the appropriate injection technique and in locations where post-injection observation and access to appropriate medical care in the case of overdose can be assured.1

However, due to the large volume of the injection2, olanzapine pamoate is intended for deep intramuscular gluteal injection only.1

Further label Information

After insertion of the needle, aspirate for several seconds to ensure no blood appears. If any blood is drawn into the syringe, discard the syringe and the dose and begin reconstitution and administration procedure again.
The injection should be performed with steady, continuous pressure.1



1. ZypAdhera [summary of product characteristics] Eli Lilly Netherland B.V., The Netherlands.

2. Beyea SC, Nicoll LH. Administration of medications via the intramuscular route: an integrative review of the literature and research-based protocol for the procedure. Appl Nurs Res. 1995;8(1):23-33. http://dx.doi.org/10.1016/S0897-1897(95)80279-7

Date of Last Review: May 01, 2019

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