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ZypAdhera® (olanzapine pamoate): Administration of Olanzapine Pamoate
Olanzapine pamoate is for deep intramuscular gluteal injection only. Do not administer intravenously or subcutaneously. For full information on reconstitution and administration please refer to the summary of product characteristics.
Based on Label Information
1confirms the final ZypAdhera
suspension volume to inject. Suspension concentration is 150 mg/ml
1. Confirm the final ZypAdhera suspension volume to inject1
volume to inject (ml)
concentration is 150 mg/ml olanzapine.
Determine which needle will be used to administer the injection to
the patient. For obese patients, the 50 mm is recommended for
the 50 mm needle is to be used for injection, attach the 38 mm safety
needle to the syringe to withdraw the required suspension volume.
▪ If the 38 mm needle is to be used for the
injection, attach the 50 mm safety needle to withdraw the required
Slowly withdraw the desired amount. Some excess product will remain
in the vial.1
Engage the needle safety device and remove needle from syringe.1
Attach the selected 50 mm or 38 mm safety needle to the syringe prior
to injection. Once the suspension has been removed from the vial, it
should be injected immediately.1
Select and prepare a site for injection in the gluteal area. DO NOT
INJECT INTRAVENOUSLY OR SUBCUTANEOUSLY.1
After insertion of the needle, aspirate for several seconds to ensure
no blood appears. If any blood is drawn into the syringe, discard the
syringe and the dose and begin reconstitution and administration
The injection should be performed with steady,