Taltz ® (ixekizumab)

This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information.For current prescribing information for all Lilly products, including Summaries of Product Characteristics, Patient Information Leaflets and Instructions for Use, please visit: www.medicines.org.uk (England, Scotland, Wales) or www.emcmedicines.com/en-GB/northernireland/ (Northern Ireland).

What to do, when a Taltz® (ixekizumab) dose is missed in adult patients with plaque psoriasis?

The Taltz European Summary of Product Characteristics does not contain a specific recommendation about what to do when a patient forgets a dose of ixekizumab.


Additional information on the missed dose 

  • The US Taltz package insert states that if a dose is missed, the dose should be administered as soon as possible. Thereafter, resume dosing at the regular scheduled time.1
  • In the ixekizumab clinical development program, ixekizumab was administered at approximately the same time each day, as much as possible.2,3
  • For the pivotal UNCOVER adult psoriasis clinical trials, injections not administered on the scheduled day were to be administered
    • within 1 to 3 days of the scheduled day during the induction period (week 0-12), and
    • within 5 days of the scheduled day after week 12.2


1Taltz [package insert]. Indianapolis, IN: Eli Lilly and Company; 2021.

2Gordon KB, Blauvelt A, Papp KA, et al; UNCOVER-1, UNCOVER-2, and UNCOVER-3 Study Groups. Phase 3 trials of ixekizumab in moderate-to-severe plaque psoriasis. N Engl J Med. 2016;375(4):345-356. http://dx.doi.org/10.1056/NEJMoa1512711

3Data on file, Eli Lilly and Company and/or one of its subsidiaries.

Date of Last Review: 15 April 2020

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