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Taltz Summary of Product Characteristics (SmPC)
Taltz® (ixekizumab): Missed Dose in patients with Psoriatic Arthritis
The Taltz European Summary of Product Characteristics does not contain a specific recommendation about what to do when a patient forgets a dose of ixekizumab.
US Taltz package insert states that if a dose is missed, the dose
should be administered as soon as possible. Thereafter, resume
dosing at the regular scheduled time.1
the ixekizumab clinical development program, ixekizumab was
administered at approximately the same time each day, as much as
the pivotal SPIRIT PsA clinical trials, injections not administered
on the scheduled day were to be administered
3 to 4 days of the scheduled day from week 0 to week 24, and
4 to 5 days of the scheduled day after week 24.3
alone or in combination with methotrexate, is indicated for the
treatment of active psoriatic arthritis in adult patients who have
responded inadequately to, or who are intolerant to one or more
disease-modifying anti-rheumatic drug (DMARD) therapies.4
Taltz [package insert]. Indianapolis, IN: Eli Lilly and Company;