Taltz ® (ixekizumab)

This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information. Please refer to the link for full prescribing information: Taltz Summary of Product Characteristics (SmPC)

Taltz® (ixekizumab): Missed Dose in Adult Patients with Plaque Psoriasis

The Taltz European Summary of Product Characteristics does not contain a specific recommendation about what to do when a patient forgets a dose of ixekizumab.

Additional Information

  • The US Taltz package insert states that if a dose is missed, the dose should be administered as soon as possible. Thereafter, resume dosing at the regular scheduled time.1

  • In the ixekizumab clinical development program, ixekizumab was administered at approximately the same time each day, as much as possible.2,3

  • For the pivotal UNCOVER adult psoriasis clinical trials, injections not administered on the scheduled day were to be administered

    • within 1 to 3 days of the scheduled day during the induction period (week 0-12), and

    • within 5 days of the scheduled day after week 12.2

Therapeutic Indication

Ixekizumab is indicated for the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy.4


1. Taltz [package insert]. Indianapolis, IN: Eli Lilly and Company; 2020.

2. Gordon KB, Blauvelt A, Papp KA, et al. Phase 3 trials of ixekizumab in moderate-to-severe plaque psoriasis. N Engl J Med. 2016;375(4):345-356. http://dx.doi.org/10.1056/NEJMoa1512711

3. Data on file, Eli Lilly and Company and/or one of its subsidiaries.

4. Taltz [summary of product characteristics]. Eli Lilly Nederland B.V., The Netherlands.

Date of Last Review: February 12, 2019

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