Do
not reuse needles. Dispose of the needle
in
a responsible manner.
Needles must
not be
shared.
Vials, cartridges and Humulin KwikPens can be used until empty,
then properly
discard.
Any
unused
medicinal
product
or
waste
material
should be disposed
of
in accordance with
local requirements.
Instructions
for use and handling
Vials
Humulin
I (isophane insulin) and Humulin M3 vial (30% soluble/70% isophane
insulin)
A
suspension for injection in a 10ml
vial
to
be
used in conjunction with an appropriate
syringe
(100
IU/ml
markings).
Humulin
S (soluble insulin) vial
A
solution for injection in a 10ml
vial
to be used in conjunction with an appropriate syringe
(100
IU/ml
markings).
KwikPen
Humulin
I KwikPen and Humulin M3 KwikPen
A
suspension
for injection in a pre-filled
/ disposable
pen
injector containing
a
3ml
cartridge.
Humulin
KwikPen
delivers
up to 60 units per dose in single
unit increments.
Cartridges
The
cartridges should only be used in conjunction with a Lilly reusable
insulin pen and should not be used with any other reusable pen, as
the dosing accuracy has not been established with other pens.
To
prevent the possible transmission of disease, each pen or cartridge
must be used by one patient only, even if the needle or needle on the
delivery device is changed.
a)
Preparing
a
dose
Vials
containing
Humulin
I or Humulin M3 formulations
should be rotated several
times
in the palms
of the
hands
before use to completely
resuspend
the
insulin, until it appears uniformly
cloudy
or
milky.
If
not,
repeat the above
procedure
until contents are mixed.
Do
not shake
vigorously
as
this may
cause
frothing,
which may
interfere
with the correct
measurement
of the dose.
Cartridges
and Humulin
KwikPens
containing
Humulin
I
or Humulin M3 formulations
should be rolled in the palms
of the hands ten
times
and
inverted
180° ten times
immediately
before
use to
resuspend
the insulin until it appears
uniformly
cloudy
or
milky.
If
not,
repeat the above
procedure until contents are mixed.
Cartridges
contain
a small
glass
bead to assist
mixing.
Do
not shake
vigorously
as
this may
cause
frothing,
which
may
interfere
with
the correct measurement
of the dose.
The
vials,
cartridges and pre-filled pens
should be examined
frequently
and
should not be used if clumps
of material
are
present
or
if
solid
white
particles
stick
to
the
bottom
or
wall
of
the
vial,
cartridge
giving
a
frosted
appearance.
Vials
and cartridges containing
Humulin
S formulation
do not require resuspension and should only
be
used
if
it is clear, colourless, with
no solid particles visible
and if it is of
water-like
appearance.
The
cartridges
are not designed
to allow
any other
insulin to be mixed
in the cartridge.
Cartridges
are
not
designed
to be refilled.
The
manufacturer's instructions with each individual pen must be followed
for loading the cartridge, attaching the needle and administering the
insulin injection.
When
using vials with a syringe: Prepare your syringe prior to injection,
as directed by your doctor or diabetes specialist nurse. Use an
insulin syringe marked for the strength of insulin being
administered.
Follow
the instructions with Human Insulins KwikPens for attaching the
needle and administering the insulin injection.
For
Human
Insulins KwikPens,
a needle must
always
be attached before priming,
dialling
and
injecting
an
insulin
dose. Human
Insulins KwikPens
should always
be primed
before each injection. Failure to prime
Human
Insulins KwikPens
may
result
in an inaccurate dose.
Mixing
of
insulins (Humulin I and Humulin S in vials only)
The
shorter acting
insulin
should
be drawn into the syringe
first, to
prevent
contamination
of the vial
by
the
longer
acting
preparation.
It
is
advisable
to inject
directly
after
mixing.
However,
if a delay
is
necessary,
a consistent routine must
be followed.
Alternatively,
a
separate syringe
or, separate cartridges
of Humulin
S and I,
can be used for
administration
of the correct
amount
of each formulation.
b)
Injecting a
dose
Inject
the correct dose of insulin, as directed
by
your
doctor or diabetes specialist nurse.
Use
of the injection sites should be rotated so that the same
is not used more
than
approximately
once
a month.
Each
pack
contains
a patient information
leaflet with instructions on how to inject insulin.
Reference
Humulin
S 100 cartridge Summary of Product Characteristics
Humulin
S 100 vial Summary of Product Characteristics
Humulin
I 100 cartridge Summary of Product Characteristics
Humulin
I 100 SPC KwikPen Summary of Product Characteristics
Humulin
I 100 SPC vial Summary of Product Characteristics
Humulin
M3 100 cartridge Summary of Product Characteristics
Humulin
M3 100 KwikPen Summary of Product Characteristics
Humulin
M3 100 vial Summary of Product Characteristics