Verzenios ® ▼ (abemaciclib)

This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information.For current prescribing information for all Lilly products, including Summaries of Product Characteristics, Patient Information Leaflets and Instructions for Use, please visit: www.medicines.org.uk (England, Scotland, Wales) or www.emcmedicines.com/en-GB/northernireland/ (Northern Ireland).

How do I manage the Verzenios® ▼ (abemaciclib) side effect diarrhoea?

At the first sign of loose stools, start treatment with anti-diarrhoeal agents such as loperamide and increase oral liquids. Dose modifications are recommended in patients who develop ≥ Grade 2 diarrhoea.

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Dose Modification and Management of Diarrhoea

Please find recommendations for dose modifications to manage diarrhoea presented in Management recommendations for diarrhoea. 

Management recommendations for diarrhoea1,2