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Abasaglar ® (basal insulin glargine)
This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information.For current prescribing information for all Lilly products, including Summaries of Product Characteristics, Patient Information Leaflets and Instructions for Use, please visit: www.medicines.org.uk (England, Scotland, Wales) or www.emcmedicines.com/en-GB/northernireland/ (Northern Ireland).
How are patients transitioned from another basal insulin to Abasaglar® (insulin glargine)?
If transitioning from another basal insulin to Abasaglar, the recommended initial Abasaglar dose is based on the insulin therapy that is being discontinued.
UK_cFAQ_BIV049_TRANSITION_TABLE
en-GB
Transitioning from another basal insulin to Abasaglar therapy
Reductions in the Abasaglar dose when transitioning from certain insulins will lower the likelihood of hypoglycemia.1,2
Please find a transition table in Transitioning From Another Basal Insulin to Abasaglar Therapy.
If transitioning from… |
To… |
Then, the recommended initial dose of Abasaglar … |
Example |
Lantus |
Abasaglar |
is the same as the Lantus dose. |
50 units of Lantus transitions to 50 units of Abasaglar |
Toujeo |
Abasaglar |
is 80% of the Toujeo dose. |
50 units of Toujeo transitions to 40 units of Abasaglar |
twice-daily NPH insulin |
once-daily Abasaglar |
is 70%-80% of the total daily NPH insulin dosage. |
25 units of NPH insulin every morning and 25 units of NPH insulin every evening, for a daily total of 50 units of NPH insulin, transitions to 35 units (70% of the NPH insulin total daily dose) or 40 units (80% of the NPH insulin total daily dose) of Abasaglar once daily |
an intermediate- or long-acting insulin other than Lantus |
Abasaglar |
may differ from the prior basal insulin dose and other concomitant antihyperglycemic medications may need to be adjusted. |
… |
Abbreviations: Abasaglar = Abasaglar® (insulin glargine) 100 units/mL; Lantus = Lantus® (insulin glargine) 100 units/mL; Toujeo = Toujeo® (insulin glargine) 300 units/mL.
References
1Abasaglar [summary of product characteristics]. Eli Lilly Nederland B.V., The Netherlands.
2Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Date of Last Review: 22 August 2022
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