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Forsteo ® (teriparatide)
Forsteo® (teriparatide): Patients with History of Lung Cancer
There is no specific information on the use of Forsteo (teriparatide) in patients with a past history of lung cancer.
In a patient with a history of lung cancer, take into consideration the risk of bone metastases, and the length of time the patient has been in remission before prescribing Forsteo.1
Relevant information from Summary of Product Characteristics
Patients with skeletal malignancies or bone metastases should be excluded from treatment with teriparatide (contraindication).2
Forsteo is contraindicated in patients with prior external beam or implant radiation therapy to the skeleton.2
Clinical trial experience
Patients with a history of carcinoma in the previous five years or with a current suspicion were excluded from participating in clinical trials with teriparatide. However, patients with excised superficial lesions of the skin and those with a history of carcinoma in situ of the cervix or uterus were allowed to participate.3
There was no apparent increase in the incidence of cancers among all study participants treated with teriparatide compared with placebo during clinical trials.3
1. File E, Deal C. Clinical update on teriparatide. Curr Rheumatol Rep. 2009;11(3):169-176. http://link.springer.com/article/10.1007/s11926-009-0023-3
3. Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Date of Last Review: March 03, 2020