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Forsteo Summary of Product Characteristics (SmPC)
Forsteo® (teriparatide): Patients with History of Cancer
Patients with skeletal malignancies or bone metastases should be excluded from treatment with teriparatide.
patient with a history of cancer, take into consideration the type of
previous cancer, the risk of bone metastases, and the length of time
the patient has been in remission before prescribing Forsteo.1
Information from Summary of Product Characteristics
with skeletal malignancies or bone metastases should be excluded from
treatment with teriparatide (contraindication).2
is contraindicated in patients with prior external beam or implant
radiation therapy to the skeleton.2
of Common Cancer that Metastasize to the Bone
cancers that metastasize to the bone, in decreasing order of
This is not an all-inclusive list; cancers not included in this list
may also have the potential to metastasize to the bone.
from Clinical Studies
with a history of carcinoma in the previous five years or with a
current suspicion were excluded from participating in clinical trials
with teriparatide. However, patients with excised superficial lesions
of the skin and those with a history of carcinoma in situ of the
cervix or uterus were allowed to participate.3
was no apparent increase in the incidence of cancers among all study
participants treated with teriparatide compared with placebo during