Prefilled insulin pens (KwikPen®, Tempo Pen®)

This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information.For current prescribing information for all Lilly products, including Summaries of Product Characteristics, Patient Information Leaflets and Instructions for Use, please visit: www.medicines.org.uk (England, Scotland, Wales) or www.emcmedicines.com/en-GB/northernireland/ (Northern Ireland).

Does the needle of the Kwikpen® or Tempo pen® normally leak insulin?

A drop of insulin at the needle tip when attaching the needle, priming the pen or after an injection is normal. If the insulin continues to leak from the needle or any other part of the pen, please contact Eli Lilly and Company.

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en-GB

Does one drop of insulin at the needle tip after an injection affect the dose?

After injection, there may be a drop of insulin at the needle tip. This is normal and does not affect the dose.1

When should the patient not use the pen?

The patient should not use the pen if any of the parts of the pen appear broken or damaged.1

Please contact the Lilly affiliate, if

  • insulin continues to leak (more than 1 drop), or
  • the insulin appears anywhere else other than at the tip of the needle.

How can the patient prevent insulin from leaking continuously from the needle?

Steps from the instructions for use that help prevent continuously leaking from the needle provides handling information that can help prevent leaking insulin from the needle.

Steps from the instructions for use that help prevent continuously leaking from the needle1

Do not store the pen with the needle attached to prevent leaking, blocking the needle, and air from entering the pen.

Prime before each injection. Priming the pen means removing the air from the needle and cartridge that may collect during normal use and ensures that the pen is working correctly.

After pushing the dose knob all the way in, continue to hold the dose Knob in and slowly count to 5 before removing the needle.

Store the pen in use at room temperature and below 30°C.

After injection, check the number in the dose window: 

  • If you see “0” in the dose window, you have received the full amount you dialled.
  • If you do not see “0” in the dose window, please refer to the user manual for next steps.

Which pens does this information apply to?

This information applies to all of Eli Lilly and Company's pre-filled pens:

  • Abasaglar 100 units/mL KwikPen2
  • Abasaglar 100 units/mL Tempo Pen3
  • Humalog 100 units/mL KwikPen4
  • Humalog Mix25 100 units/mL KwikPen4 
  • Humalog Mix50 100 units/mL KwikPen4
  • Humalog 100 units/mL Junior  KwikPen5
  • Humalog 200 units/mL KwikPen6
  • Humalog 100 units/mL Tempo Pen7
  • Humulin I 100 units/mL KwikPen8 
  • Humulin M3 100 units/mL KwikPen8 
  • Lyumjev 100 units/mL KwikPen9
  • Lyumjev 200 units/mL KwikPen10
  • Lyumjev 100 units/mL Junior KwikPen11
  • Lyumjev 100 units/mL Tempo Pen12

For further information about a specific pre-filled pen, please refer to the corresponding user manual, patient leaflet and summary of product characteristcs.

References

1Data on file, Eli Lilly and Company and/or one of its subsidiaries.

2Abasaglar 100 units/mL KwikPen [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

3Abasaglar 100 units/mL Tempo Pen [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

4Humalog® 100 units/ml KwikPen® [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

5Humalog® 100 units/ml Junior KwikPen® [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

6Humalog® 200 units/ml KwikPen® [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

7Humalog® 100 units/ml Tempo Pen [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

8Humulin® 100 IU/ml KwikPen® [instructions for use]. Eli Lilly and Company Limited, United Kingdom.

9Lyumjev® 100 units/ml KwikPen® [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

10Lyumjev® 200 units/ml KwikPen® [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

11Lyumjev® 100 units/ml Junior KwikPen® [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

12Lyumjev® 100 units/ml Tempo Pen [instructions for use]. Eli Lilly Nederland B.V., The Netherlands.

Date of Last Review: 18 October 2022


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