Cymbalta ® (duloxetine)

This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information.For current prescribing information for all Lilly products, including Summaries of Product Characteristics, Patient Information Leaflets and Instructions for Use, please visit: (England, Scotland, Wales) or (Northern Ireland).

Cymbalta® (duloxetine): Opening or Splitting a Capsule

Opening or splitting the Cymbalta capsule is not recommended. As per the package leaflet, patients should swallow the capsule whole with a drink of water.


Further details

Duloxetine should be swallowed whole. Capsules should not be chewed or crushed. Capsules should not be opened nor its contents sprinkled on food or mixed with liquids. All of these might affect the enteric coating.1


1Cymbalta [package insert]. Indianapolis, IN: Eli Lilly and Company; 2019.

Date of Last Review: 31 October 2019

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