Warnings and precautions: Selpercatinib and increased hepatic enzymes
Dosing modifications for increased AST and/or ALT
Increased ALT and AST with selpercatinib in clinical trials
Treatment-emergent adverse events of increased ALT and AST with selpercatinib
Serious adverse events of increased ALT and AST with selpercatinib
Time to onset of increased ALT and AST in selpercatinib trials
Dosage modifications for increased ALT and AST in selpercatinib studies
Additional hepatic enzyme abnormalities in LIBRETTO-001
Dosage modifications for other hepatic abnormalities in selpercatinib trials
Hepatic function criteria in selpercatinib clinical trials