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Cialis Summary of Product Characteristics (SmPC)
Clinical trials of tadalafil for the once daily treatment of ED and/or signs and symptoms of BPH did not study the effect of skipping doses.
Effect
of skipping dose(s)
Tadalafil
dosed once daily has been studied in clinical trials for the
treatment of erectile
dysfunction
(ED), the signs and symptoms of benign prostatic hyperplasia (BPH),
and both ED and signs and symptoms of BPH. Once daily dosing allows
the achievement of steady state plasma concentration and clinical
efficacy was assessed following daily dosing (Cialis SmPC).
The
impact of a missed day of therapy has not been studied, but impact on
efficacy is likely to vary by patient. Some patients may notice
reduced efficacy from missing a single dose, while others may not
(Data on file).
REFERENCES
CIALIS
EU Summary of Product Characteristics [SmPC], Utrecht, The
Netherlands: Eli Lilly Nederland B.V.
Data
on file, Eli Lilly and Company and/or one of its subsidiaries.
Date of Last Review:November 11, 2019
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