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Cialis ® (tadalafil)
This information is intended for UK registered healthcare professionals only as a scientific exchange in response to your search for information. Please refer to the link for full prescribing information:
Cialis Summary of Product Characteristics (SmPC)
Cialis (tadalafil): Effect of skipping dose
Clinical trials of tadalafil for the once daily treatment of ED and/or signs and symptoms of BPH did not study the effect of skipping doses.
Effect of skipping dose(s)
Tadalafil dosed once daily has been studied in clinical trials for the treatment of erectile
dysfunction (ED), the signs and symptoms of benign prostatic hyperplasia (BPH), and both ED and signs and symptoms of BPH. Once daily dosing allows the achievement of steady state plasma concentration and clinical efficacy was assessed following daily dosing (Cialis SmPC).
The impact of a missed day of therapy has not been studied, but impact on efficacy is likely to vary by patient. Some patients may notice reduced efficacy from missing a single dose, while others may not (Data on file).
REFERENCES
CIALIS EU Summary of Product Characteristics [SmPC], Utrecht, The Netherlands: Eli Lilly Nederland B.V.
Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Date of Last Review: November 11, 2019
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